People - Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum (SCTIMST)

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श्री चित्रा तिरुनाल आयुर्विज्ञान और प्रौद्योगिकी संस्थान, त्रिवेंद्रम

विज्ञान एवं प्रौद्योगिकी विभाग, भारत सरकार के अधीन एक राष्ट्रीय महत्व का संस्थान

Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum

An Institution of National Importance, Department of Science and Technology, Govt. of India

HOSPITAL

BMT

AMCHSS

ACADEMIC

JOURNAL

Dr. Bijulal S.

Professor

Phone : 91 9446590185

Email :

Academic Qualification Professional Record Publications

Academic Qualifications

DM Cardiology( SCTIMST 2005)

MD Internal medicine( MG University 2002)

MBBS (University of Kerala1997)

Professional Record

Professor, Cardiology, SCTIMST 2018 onwards

Additional Professor, Cardiology, SCTIMST 2015-18

Associate Professor, Cardiology, SCTIMST, 2012-15

Senior Interventional Cardiologist, HMCC, Manjeri , 2014-2015( On leave from SCTIMST)

Assistant Professor, Cardiology,SCTIMST, 2008-2012

Senior Consultant Cardiologist, IGMH, Male' , Maldives , 2008- 2009 (On deputation from SCTIMST)

Adhoc Consultant, Cardiology, SCTIMST, 2007-2008

Honors

Commonwealth Fellowship in Cardiology ( Leeds teaching hospitals, UK ) 2012-2013

Fellowship in interventional cardiology, SCTIMST 2006

Awards

Honoured by the institute for performing the first TAVR in a Government institute in South India 2018

Area of Interest

Structural heart intervention- Trans catheter valve replacement, Large vessel stenting, Para valvar leak closure

Complex coronary interventions - CTO , left main, rotablation , high risk coronary intervention, coronary imaging

Collaboration

Division of polymeric medical devices, BMT wing, SCTIMST

Division of artificial internal organs, BMT Wing, SCTIMST

Division of extracorporeal devices, BMT wing, SCTIMST

Biorad Medisys Pvt Ltd, Bangalore

Terumo India Pvt Ltd, New Delhi

Merill Life Scinces Pvt Ltd, Vapi, India

Current Activities

Clinical- Structural heart interventions ( TAVI), Complex coronary interventions, Out patient clinic, Intervention clinic, Ward rounds

Academic - Training interventional fellows and residents in intervention

Research- Collaborative research projects with BMT wing, Indian medical devices companies and multi-national medical devices companies

Patent Application: Implantable Atrial Septal Defect occlusion device with woven central section on left atrial flange. Appl. No: 201741036490, Date: 13.10.2017 Inventors: SUJESH S., JIJO JERARD, LIJI G.V., DR. BIJULAL S.

Design Application: Implantable atrial septal defect occlusion device with woven central section on left atrial flange. Design No: 300221, Date: 8 Dec 2017. Designers: : SUJESH S., JIJO JERARD, LIJI G.V., DR. BIJULAL S.

Fellowships

Commonwealth fellowship in Cardiology( Trans-catheter Aortic Valve Implantation), 2012-3013, Leeds General Infirmary, Leeds, UK

Membership

Member, Cardiological society of India

Member, Pediatric cardiac society of India

Member, Interventional Coronary council of Kerala

Member, Association of Physicians of India

Member, Indian Medical Association

On-going Projects

Novel technique of developing trans-catheter heart valve from human homograft for per-cutaneous pulmonary valve replacement. Principal Investigator. Funding agency- BIRAC, Govt of India

Development of a semi-automatic angiography system for facilitating coronary angiography and angioplasty. Co-PI- Technology development Fund, SCTIMST

Development of nitinol based occlusion device for non-surgical closure of the atrial septal defect. Principal Investigator. Funding agency- Technology development Fund, SCTIMST

MyVal 1- A prospective single-arm, multicentric, open-label study of the MyVal TAVR system in the treatment of severe symptomatic native aortic valve stenosis ?CoPI (Site). Funding agency- Merill Life Sciences Pvt Ltd

Projects Completed

Prospective, Single-arm, Multi-center, Observational Registry to further Validate Safety and Efficacy of the Ultimate DES in Real-World Patients. Principal Investigator (site). Funding agency- Terumo India Ltd

Practical evaluation of FFR and its associated alternate indices during routine clinical procedures ? CoPI ( Site). Funding agency ?Abbott India Ltd

Association between gender, process of care measures, and outcomes in ACS in India: results from the detection and management of coronary heart disease (DEMAT) registry. - Principal investigator (Site).

Magnitude of ventricular unloading in single ventricle of left ventricular morphology following Bi- directional Glenn or Fontan operation ?A 3D Echocardio graphic study, Principal investigator.

Professional Experience

Co-ordinate and perform TAVI in the institute for the last 5 years. The institute is one of the leading center in Kerala for this procedure . Was the site co-ordinator for the first in man study using Indigenously developed MyVal TAVR system from Meill life sciences. Performs 10-15 TAVI each year. Performs complex coronary interventions in the institute which have changed the outcome in many patients.

Desertations Supervised

Early and late outcomes after Transcatheter Aortic Valve Implantation

Long term outcomes of percutaneous coronary intervention in patients with previous coronary artery bypass graft surgery

Clinical profile and outcomes of cardiomyopathy in children

Training

Each year train one or two fellow in all aspects of coronary intervention

Major Achievements

Initiated and established TAVI in the institute

Initiated percutaneous pulmonary valve replacement in the institute

Initiated and established ductal stenting in the institute

Initiated fetal echocardiography in the institute

Established large vessel stenting in the department

Consultancies

National board of examinations- Site inspector

National board of examinations- Thesis assessor

Research

Completed Assignments

Team

Structural heart disease intervention team

Coronary intervention team

Presentations

Acute stent thrombosis- OCT into the ACT. Bhagwati Pant, Walse, Bijulal Sasidharan. SCIP India 6th annual national conference. Thiruvananthapuram 29-30 Oct 2022

Acute severe MR during TAVR. Bhagwati Pant, Walse, Bijulal Sasidharan. NIC mid term meet Ahmedabad 17-19 June 2022

Acute coronary occlusion during TAVR- Bailout strategy .Bhagwati Pant, Walse, Bijulal Sasidharan. TCT 2022. Boston, USA Sept 2022 ( Virtual case presentation )

Acute mitral regurgitation during TAVR. What is the mechanism? Bhagwati Pant, Walse, Bijulal Sasidharan ACC Middle east, Dubai 6-8 Oct 2022

Surgically denied calcified left main stenosis. Can PCI save the day ? Rohit Walse, Bhagwati Pant, Bijulal Sasidharan. SCIP India 6th annual national conference. Thiruvananthapuram 29-30 Oct 2022

Device embolization during TAVR : Expect the unexpected. Rohit Walse, Bhagwati Pant, Bijulal Sasidharan India Valves Goa 11 Sept 2022

CHIP PCI without hemodynamic support- A real world scenario. Rohit Walse, Bhagwati Pant, Bijulal Sasidharan .NIC mid term interventional meet. Ahmedabad 17-19 June 2022

"Perfection is the enemy of good: A bail out TAVR in TAVR". Rohit Walse, Bhagwati Pant, Bijulal Sasidharan. Asian Pacific society of intervention al cardiology AICT Singapore Oct 6-8 2022

Trans catheter pulmonary valve replacement- London valve 2018

Invited talks

TAVI in bicuspid anatomy- Indian college of Cardiology .National conference . Nov 12, 2022. Trivandrum

TAVI- Steps Sept 3, 2022, ICCK Annual meet. Kozhikode. Kerala

Echocardiography in TAVI - IAE Kerala chapter meet. March 26, 2022

TAVI in Bicuspid anatomy- 31.7.2021. Amrita Institute online symposium

How to optimize TAVI with supra-annular valve ? TAVI Master class 17.7.21 (online meeting)

Practical aspects of TAVI in bicuspids ?TAVI Master class ( online meeting) Feb 21, 2021

No. of Publications

No. of Books Authored/ Edited

1. Bijulal S. Yoga, Meditation and Healthy Heart, Principles and Evidence. ln Cardiovascular Diseases: Nutritional and Therapeutic interventions. Ed by Maulik N.561-576' CRC press 2013.

Select Publications

Technology Transferred

Atrial septal occluder technology transferred to Bioradmedisys Pvt Ltd

Publications

Article

Ankur Agarwal , Bijulal Sasidharan , Ajitkumar Valaparambil, Early and late outcomes after transcatheter aortic valve implantation in Indian subpopulation, Indian Heart Journal, 2022, , 10.1016/j.ihj.2022.09.002

Kawoos GM, Nair KKM, Sasidharan B, Valaparambil AK., Valvular and supravalvular aortic stenosis fifteen years after coronary artery bypass grafting in a patient with familial hypercholesterolaemia., Acta Cardiol., 2022,

Walad S, Harikrishnan KN, Gopalakrishnan A, Sivasubramonian S, Sasidharan B., Technical considerations of coarctation stenting in double-barreled aorta - A persistent fifth arch mimic., Ann Pediatr Cardiol., 2021,

Kartik SV, Sasidharan B, Gopalakrishnan A, Kurup HKN, Krishnamoorthy KM, Sasikumar D, Thulaseedharan JV, Valaparambil A, Tharakan J, Sivasubramonian S., A Comparative Study of Invasive Modalities for Evaluation of Pulmonary Arteriovenous Fistula after Bidirectional Glenn Shunt., Pediatr Cardiol., 2021,

Sivakumar K, Sagar P, Qureshi S, Promphan W, Sasidharan B, Awasthy N, Kappanayil M, Suresh PV, Koneti NR., Outcomes of Venus P-valve for dysfunctional right ventricular outflow tracts from Indian Venus P-valve database., Ann Pediatr Cardiol, 2021,

Gopalakrishnan A, Sasidharan B, Menon S, Krishnamoorthy KM., Drug-eluting stent for acute Blalock-Taussig shunt thrombosis in a child-case report., Egypt Heart J., 2021,

Harikrishnan S, Muralidharan R, Mani A, Sanjay G, Prasad S, Bijulal S, Sivasankaran S, Valaparambil AK., Long term outcomes after bare metal stent implantation., Indian Heart J, 2021,

Nair KKM, Valaparambil A, Sasidharan B, Ganapathi S, Gopalakrishnan A, Namboodiri N, Sivadasanpillai H., Immediate, early and mid-term outcomes following balloon mitral valvotomy in patients having severe rheumatic mitral stenosis with significant tricuspid regurgitation., Indian J Thorac Cardiovasc Surg, 2020,

Sukulal K, Mohanan Nair KK, Sasidharan B, Valaparambil A, Ganapathi S, Sivasubramanian S, Sivadasanpillai H., Implication of d-dimer in rheumatic severe mitral stenosis - A tertiary centre study., Indian Heart J., 2020,

Sasikumar D, Sasidharan B, Rashid A, Ayyappan A, Goplakrishnan A, Krishnamoorthy KM, Sivasubramonian S., Early and late outcome of covered and non-covered stents in the treatment of coarctation of aorta- A single centre experience., Indian Heart J., 2020,

more...

Babu S, Molli K, Menon S, Gohain D, Sasidharan B, Koshy T., An Intraoperative Transesophageal Echocardiographic Artifact Mimicking a Tear in Left Ventricle Apex In a Case of Massive Pericardial Effusion., J Cardiothorac Vasc Anesth., 2019,

Mohanan Nair KK, Valaparambil A, Sasidharan B, Ganapathi S, Gopalakrishnan A, Namboodiri N, Sivasubramanian S, Sivadasanpillai H., Immediate and late clinical outcomes of balloon mitral valvotomy based on immediate postballoon mitral valvotomy mitral valve area & percentage gain in mitral valve area-A tertiary centre study., Indian Heart J., 2018,

Sasikumar D, Menon S, Baruah SD, Dharan BS, Gohain D, Sasidharan B, Sivasankaran S., Anomalous Left Coronary Artery From Pulmonary Artery in a Baby With Pulmonary Atresia, Intact Ventricular Septum., Ann Thorac Surg., 2018,

Sasikumar D, Sasidharan B, Ayyappan A., Haemodynamic consequences following closure of an Abernethy malformation in a patient following a total cavopulmonary shunt., Cardiol Young., 2018,

Gopalakrishnan A, Sasidharan B, Tharakan J, Valaparambil A., Left atrial outflow obstruction in double-outlet right atrium., Asian Cardiovasc Thorac Ann., 2018,

Sivasubramonian S, Gopalakrishnan A, Sasidharan B, Valaparambil A., Role of Diastology in Transcatheter Aortic Valve Implantation., J Invasive Cardiol, 2018,

Sasikumar D, Sasidharan B, Ayyappan A, Gopalakrishnan A, Krishnamoorthy KM., Coronary-to-pulmonary artery collaterals in pulmonary atresia., Ann Pediatr Cardiol., 2018,

Prasad S, Harikrishnan S, Sanjay G, Abhilash SP, Bijulal S, Mohanan Nair KK, Tharakan J, Ajit Kumar VK., Clinical Outcomes of patients with coronary artery disease who underwent FFR evaluation of intermediate coronary lesionS- COFFRS study., Indian Heart J., 2017,

Bijulal S, Sasikumar D, Rashid A, Unexpected complication of uncovered aortic end in ductal stenting., Cardiol Y, 2017,

Sasikumar D, Sasidharan B, Dharan BS, Gopalakrishnan A, Krishnamoorthy KM, Sivasankaran S, Quantification of ventricular unloading by 3D echocardiography in single ventricle of left ventricular morphology following superior cavo-pulmonary anastomosis and Fontan completion - a feasibility study., Ann Pediatr Cardiol, 2017,

Sasikumar D, Sasidharan B, Dharan BS, Sivasankaran S, Krishnamoorthy KM., Imaging the elusive anomalous origin of left coronary artery from pulmonary artery., Echocardiography., 2017,

Gopalakrishnan A, Subramanian V, Sasidharan B, Sasikumar D, Krishnamoorthy KM, Dharan BS, Valaparambil A., A rare variant of intracardiac total anomalous pulmonary venous connection., Rev Port Cardiol., 2017,

Behera DR, Nair KKM, Sasidharan B., Ductal aneurysm with postsubclavian coarctation of aorta in an adult., Ann Pediatr Cardiol., 2017,

Gopalakrishnan A, Sasidharan B, Krishnamoorthy KM, Sivasubramonian S, Dharan BS, Mathew T, Titus T, Valaparambil A, Tharakan J., Left ventricular regression after balloon atrial septostomy in d-transposition of the great arteries., Eur J Cardiothorac Surg., 2016,

Gopalakrishnan A, Sasidharan B, Krishnamoorthy KM., Balloon Atrial Septostomy in Congenital Heart Disease., Circ J., 2016,

Krishnamoorthy KM, Bijulal S, Gopalakrishnan A., Severe aortic regurgitation during percutaneous closure of ventricular septal defect., Int J Cardiol, 2016,

Deepa Sasikumar, Bijulal Sasidharan, Sivasankaran Sivasubramanian, Demonstration of circular shunt in fetal Ebstein anomaly, Ann pediatr cardiol, 2015, 8(3)

Sundaram PS, Sukulal K, Bijulal S, Tharakan JA, Cervical origin of left subclavian artery: A rare anomaly., Ann Pediatr Cardiol, 2014, 7(3):227-9, http://www.ncbi.nlm.nih.gov/pubmed/25298702

Sasikumar D, Sasidharan B, Tharakan JA, Dharan BS, Mathew T, Karunakaran J, Early and 1-year outcome and predictors of adverse outcome following monocusp pulmonary valve reconstruction for patients with tetralogy of Fallot: A prospective observational study., Ann Pediatr Cardiol, 2014, 7(1), http://www.ncbi.nlm.nih.gov/pubmed/24701078

Raghuram KA, Bijulal S, Krishnamoorthy KM, Tharakan JA, Regression of pulmonary vascular disease after therapy of Abernethy malformation in visceral heterotaxy, Pediatr Cardio, 2013, 34(8), http://www.ncbi.nlm.nih.gov/pubmed/22843201

Choudhary D, Sivasankaran S, Venkateshwaran S, Sasidharan B., Cor triatiratum dexter: a rare cause of isolated right atrial enlargement., Pediatr Cardiol., 2013, 34(1), http://www.ncbi.nlm.nih.gov/pubmed/22850970

Deepa S, Bijulal S, Baiju DS, Thomas M, Septal course of left anterior descending artery from the right aortic sinus in tetralogy of Fallot: a benign anomaly and important lessons learned., Pediatr Cardio, 2013, 34(1):200-2, http://www.ncbi.nlm.nih.gov/pubmed/22847730

Mahesh Kumar S, Bijulal S, Krishnamoorthy KM, Percutaneous transjugular device closure of postoperative residual atrial septal defect., J Invasive Cardiol, 2013, 25(4, http://www.ncbi.nlm.nih.gov/pubmed/23549502

Kumar SM, Subramanian V, Bijulal S, Krishnamoorthy KM, Sivasankaran S, Tharakan JA, Percutaneous closure of a moderate to large tubular or elongated patent ductus arteriosus in children younger than 3 years: is the ADO II appropriate?, Ann Pediatr Cardio, 2013, 34(7):1661-7, http://www.ncbi.nlm.nih.gov/pubmed/23591801

Kumar SM, Bijulal S, Sivasankaran S, Unusual association of aortic valve stenosis with ventricular septal defect and pulmonary atresia: Differentiation from truncus arteriosus with truncal valve stenosis, Ann Pediatr Cardio, 2013, 87-9, http://www.ncbi.nlm.nih.gov/pubmed/23626446

Sukulal K, Bijulal S, Tharakan JA, Differential diagnosis of vascular structures in relation to upper ascending aorta: The retro-aortic innominate vein., Ann Pediatr Cardio, 2013, 6(1):97-8, http://www.ncbi.nlm.nih.gov/pubmed/23626450

Mahesh Kumar S, Venkateshwaran S, Sasidharan B, Krishnamoorthy KM, Sivasubramonian S, Tharakan JA., Real-time 3-dimensional transesophageal echocardiography-guided device closure of coronary arteriovenous fistula., J Am Coll Cardiol, 2013, 61(13), http://www.ncbi.nlm.nih.gov/pubmed/23500271

Nair KK, Pillai HS, Titus T, Varaparambil A, Sivasankaran S, Krishnamoorthy KM, Namboodiri N,Sasidharan B, Thajudeen A, Ganapathy S, Tharakan J., Persistent pulmonary artery hypertension in patients undergoing balloon mitral valvotomy, Pulm Circ, 2013, 3(2), http://www.ncbi.nlm.nih.gov/pubmed/24015345

Singla R, Sasidharan B., "Vieussens ring" from isolated conus artery., Indian Heart J, 2013, 65(4), http://www.ncbi.nlm.nih.gov/pubmed/23993016

Pagidipati NJ, Huffman MD, Jeemon P, Gupta R, Negi P, Jaison TM, Sharma S, Sinha N, Mohanan P, Muralidhara BG, Bijulal S, Sivasankaran S, Puri VK, Jose J, Reddy KS, Prabhakaran D, Association between gender, process of care measures, and outcomes in ACS in India: results from the detection and management of coronary heart disease (DEMAT) registry., PLoS One, 2013, 8(4):e62061, http://www.ncbi.nlm.nih.gov/pubmed/23637963

Sundaram PS, Narayan GS, Prabhu MA, Bijulal S, Sanjay G, Namboodiri KK, Kapilamoorthy TR, Tharakan JA, An unusual cause for unruptured sinus of valsalva aneurysm, Indian Heart J, 2013, 65(4):484-7, http://www.ncbi.nlm.nih.gov/pubmed/23993017

Chaurasia AK, Harikrishnan S, Bijulal S, Choudhary D, Tharakan J, Cardiac rhabdomyoma in familial tuberous sclerosis., J Cardiovasc Thorac Res, 2013, 5(2):71-2, http://www.ncbi.nlm.nih.gov/pubmed/24251015

Nair KK, Ganapathi S, Sasidharan B, Thajudeen A, Pillai HS, Tharakan J, Titus T, Kumaran AV, Sivasubramonian S, Krishnamoorthy KM., Asymptomatic right ventricular dysfunction in surgically repaired adult tetralogy of fallot patients., Ann Pediatr Cardiol, 2013, 6(1), http://www.ncbi.nlm.nih.gov/pubmed/23626431

Subramanian V, Kavassery MK, Sivasubramonian S, Sasidharan B, Percutaneous device closure of persistent ductus venosus presenting with hemoptysis., Ann Pediatr Cardiol, 2013, 6(2), http://www.ncbi.nlm.nih.gov/pubmed/24688239

Chaurasia AK, Harikrishnan S, Bijulal S, Krishnamoorthy KM, Sivasankaran S, Tharakan JA, Usefulness of Doppler derived end diastolic flow gradient across the patent ductus arteriosus in selecting coils for ductal occlusion, Pediatr Cardio, 2012, 33(2, http://www.ncbi.nlm.nih.gov/pubmed/21968576

Shunmugasundaram P, Bijulal S, Titus T, Tharakan JA, Crisscross pulmonary artery with double aortic arch: an unusual association., Pediatr Cardio, 2012, 33(5), http://www.ncbi.nlm.nih.gov/pubmed/22411714

Nair KK, Pillai HS, Thajudeen A, Krishnamoorthy KM, Sivasubramonian S, Namboodiri N,Sasidharan B, Ganapathy S, Varaparambil A, Titus T, Tharakan J., Immediate and long-term results following balloon mitral valvotomy in patients with atrial fibrillation, Clin Cardiol, 2012, 35(12):, http://www.ncbi.nlm.nih.gov/pubmed/23124930

Nair KK, Pillai HS, Thajudeen A, Tharakan J, Titus T, Valaparambil A, Sivasubramonian S, Mahadevan KK, Namboodiri N, Sasidharan B, Ganapathi S., Comparative study on safety, efficacy, and midterm results of balloon mitral valvotomy performed with triple lumen and double lumen mitral valvotomy catheters., Catheter Cardiovasc Interv, 2012, 80(6), http://www.ncbi.nlm.nih.gov/pubmed/22566347

Harikrishnan S, Bijulal S, Krishnakumar N, Ajithkumar VK., Combined mitral and pulmonary valvotomy with Inoue balloon in rheumatic quadrivalvular disease., J Heart Valve Dis, 2011, 20(1), http://www.ncbi.nlm.nih.gov/pubmed/21404911

Bijulal S, Krishnamoorthy KM, Sivasankaran S, Retroaortic coronary artery: possible contraindication for device closure of atrial septal defect., Pediatr Cardio, 2011, 32(7), http://www.ncbi.nlm.nih.gov/pubmed/21656234

Gupta SK, Sivasankaran S, Bijulal S, Tharakan JM, Harikrishnan S, Ajit K, Trans-catheter closure of atrial septal defect: Balloon sizing or no Balloon sizing - single centre experience, Ann Pediatr Cardiol, 2011, 4(1), http://www.ncbi.nlm.nih.gov/pubmed/21677801

Sundaram PS, Bijulal S, Tharakan JA, Antony M, Kodamaea ohmeri tricuspid valve endocarditis with right ventricular inflow obstruction in a neonate with structurally normal heart., Ann Pediatr Cardiol, 2011, 4(1)

Book Chapter

Bijulal S., Yoga, Meditation and Healthy Heart, Principles and Evidence. CRC press 2013, ln Cardiovascular Diseases: Nutritional and Therapeutic interventions. Ed by Maulik N.561-576, 2013,