Dr. G. Srinivas
Scientist 'G' & Acting Head
Phone : 0471 2524689 (O), 85475 47918 (M)

PhD, Cancer Research ; Regional Cancer Centre, Thiruvananthapuram ; 2001

MSc Medical Biochemistry ; JIPMER, Pondicherry ; 1994

Scientist G & Head; July 2019 Onwards

Scientist F & Acting Head, July 2018- June 2019

Scientist F, July 2015- June 2018

Scientist E, Oct 2014- June 2015

ICMR International Fellow, Endocrinology, Diabetes, Metabolism and Nutrition; Mayo Clinic, Rochester, USA; Mar 2014- Sep 2014

Scientist E, July 2012- Feb 2014

Scientist D, July 2010- June 2012

IUSSTF Research Fellow, Endocrinology, Diabetes, Metabolism and Nutrition ; Mayo Clinic, Rochester, USA ; July 2009- July 2010

Scientist D, June 2008- July 2009

Scientist C, Department of Biochemistry, June 2004- June 2008

Scientist B, Division of Cancer Biology ; Rajiv Gandhi Centre for Biotechnology ; Sept 2000- May 2004

Lecturer & Head, Dept of Biochemistry ; NSS College, Pandalam, Dec 1996- August 2000

Junior Research Fellow (UGC), Division of Lab Medicine and Tumor Biology ; Regional Cancer Centre ; Oct 1994- Nov 1996

Awarded the Japanese Travel Grant to participate and present a paper at the First Indo Japan Cancer Symposium held during July 24-26, 2023 at Cancer Research Institute, Kanazawa University, Japan.

Awarded DST international Travel Grant to participate and present a paper at the 78th American Diabetes Association held during Jun 22-26, 2018, at Orlando, USA.

Awarded Institutional Travel Grant for attending the 100th International Workshop on High Resolution Respirometry, O2k-Fluorometry and TPP, 2015 April 09-14 Schrocken, Vorarlberg, Austria

Awarded UGC-CSIR/NET JRF-1993; MSc Second Rank- JIPMER-1994

Awarded DST International Travel Grant to participate and present a paper in the "International Phytochemical Society of Europe symposium on Natural Products and Cancer Therapy" held at Naples, Italy during 22-26 September, 2008 and invited to participate and present a poster at "Ehrlich II- World Conference on Magic Bullets" held at Nurnberg, Germany during 3-5 October, 2008.

Clinical and Experimental Oncology, Regulation of Autophagy, Cardiac changes during diabetes, Risk factors in dementias

Awarded the "IndoUS Science and Technology Forum Research Fellowship" (2009-10) for a period of one year to work Division of Endocrinology, Diabetes, Metabolism and Nutrition at Mayo Clinic, Rochester, USA.

Indian Council for Medical Research (ICMR) International Fellowship (2013-14) to work at Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, MN, USA.

Member, National Academy of Medical Sciences, India

Life Member, Society for Biotechnologists (India)

Life Member, International Academy of Cardiovascular Sciences (India Section)

Life Member, International Society for Heart Research (India Section)

Life Member, Society for Mitochondrial Research & Medicine, India

Life member, Society for Evolutionary and Integrative Biology, India

Member, Board of Studies (Medical Biochemistry), Kannur University, Kannur

Comparing mitochondrial function and dynamics in atrial tissue of patients undergoing Cardiopulmonary Bypass Surgery and Aortic Valve Repair replacement surgery; 2022-2025, 37.63 Lakhs, SERB

Molecular mechanism of stress-induced NLRP3 activation and neuro inflammation by macrophages in presence of amyloid-beta in Alzheimer disease; 2021- 2024, 33.15 Lakhs, ICMR

Article

1
Mahalaxmi Ganjoo, Ashok Sivasailam, Arun Gangadharan, Srinivas Gopala., Albumin binds to uncoupler CCCP to diminish depolarization of mitochondria., Toxicology In Vitro., 2022, 80
2
Nandini Ravikumar Jayakumari, Raji Sasikala Rajendran, Harikrishnan Vijayakumar Sreelatha, Srinivas Gopala., Honokiol regulates mitochondrial substrate utilization and cellular fatty acid metabolism in diabetic mice heart., Eur J Pharmacol,, 2021, 896:
3
Raji Sasikala Rajendran, Nandini Ravikumar Jayakumari, Ashok Sivasailam, Anand Chellappan Reghuvaran, Vivek Velayudan Pillai, Jayakumar Karunakaran, Harikrishnan Vijayakumar Sreelatha, Shankarappa Manjunatha, Srinivas Gopala., Diminished substrate-mediated cardiac mitochondrial respiration and elevated autophagy in adult male offspring of gestational diabetic rats., IUBMB,, 2021, 73: 676-689, .
4
Dhanya Krishnan, Ramsekhar Menon, Srinivas Gopala., SHARPIN: Role in Finding NEMO and in Amyloid Beta Clearance and Degradation (ABCD) Pathway in Alzheimer???s Disease?, Cellular and Molecular Neurobiology, 2022, 42: 1267-1281,
5
Anand CR, Bhavya Bharathan, Jayakumar K, Harikrishnan VS, Srinivas Gopala., Inorganic nitrite alters mitochondrial dynamics via Drp1 activation without modifying cell death and mitochondrial respiration in cardiomyoblasts under hyperglycemia., Toxicology In Vitro, 2021, 70
6
Bhavya Bharathan, H V Easwer, George C Vilanilam, Sreelakshmi K, Anand CR, Madhusoodanan UK, Leena Issac, Padmakrishnan CJ, Girish R Menon, Krishnakumar K, Rajalakshmi, Deepti AN, Srinivas Gopala., MutT Homolog 1 has multifaceted role in glioma and is under the apparent orchestration by Hypoxia Inducible Factor1 alpha., Life Sciences, 2021, 264:
7
Revathy Nadhan, Dipyaman Patra, Neethu Krishnan, Arathi Rajan, Srinivas Gopala, Dashnamoorthy Ravi, Priya Srinivas., Perspectives on mechanistic implications of ROS inducers for targeting viral infections., Eur J Pharmacol, 2020, 890:
8
Gurpreet Singh, Srinivas Gopala, Jyothi EK, Gayathri LK, Rakhal Gaitonde, Biju Soman., The Sree Chitra experience in containing the first outbreak of Covid-19 in a healthcare setting in India., Indian Journal of Public Health,, 2020, 64: S241-242,
9
Soumya Krishnamoorthy, Deepa Damayanthi, Srinivas Gopala, Rejith Paul, Sylaja PN., High-sensitivity C-reactive protein and lipoprotein-associated phospholipase A2 in predicting recurrence and severity of stenosis in symptomatic intracranial atherosclerotic disease., Current Proteomics,, 2020, 17: 1-6,
10
Nandini R J, Raji S R, Ashok S, Surabhi SV, Saurabh N, Manjunatha S, Vivek V Pillai, Jayakumar K, Srinivas Gopala., Impaired substrate mediated cardiac mitochondrial complex 1 respiration with unaltered regulation of fatty acid metabolism and oxidative stress status in type 2 diabetic heart., J of Diabetes,, 2020, 12: 542-555,