Dr. Madhusoodanan U. K.
Assistant Professor
Phone :
0471-2524478 (O), 8157897692

PhD-Department of Biochemistry, Indian Institute of Science, Bangalore, 2003-2009

MSc-Medical Biochemistry, KMC Manipal, Manipal University (MAHE), 1999-2002

BSc-Microbiology, Kannur University, 1996-1999

Assistant Professor - Department of Biochemistry, SCTIMST, October 2017-

Research Scientist - Molecular Oncology, MVRCCRI, Calicut, 2017

Post Doctoral fellow - IFOM-The FIRC Institute of Molecular Oncology, MIlan, Italy- 2009-2016

JRF-NET CSIR and ICMR - 2003-2009

Invited speaker in international conferences

Genetic basis of inherited disorders

Circulating exosomal-miRNAs

Proteins post Translational modifications such as Ubiquitination, SUMOylation, and Phosphorylation

Post doctoral fellowship funded by European Research Council (ERC-2009-StG ERC-SG) "Regulatory mechanisms coordinating replication integrity and intra-S repair"

Welcome trust Visiting fellow (February to April 2010), NCBR, Masaryk University, Brno, Czech Republic

Life membership of Society of Biological Chemists (SBC, India)

Article

1
Sebesta M, Madhusoodanan Urulangodi, Stefanovie B, Szakal B, Pacesa M, Lisby M, Branzei D, Krejci L, Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains, Nucleic Acids Res., 2017, 45(1):215-230, https://www.ncbi.nlm.nih.gov/pubmed/27694623
2
Madhusoodanan Urulangodi, Szakal B, Branzei D, SUMO-Mediated Local Control of Recombination, Cell Cycle, 2016, 15(2); 160-161, https://www.ncbi.nlm.nih.gov/pubmed/26587752
3
Madhusoodanan Urulangodi, Dhanaraju R, Gupta K, Roy RP,Bujnicki J, Rao DN, Asymmegric DNA Methylation by Dimeric EcoP15I DNA Methyltransferase, Biochimie , 2016, 128-129; 70-82, https://www.sciencedirect.com/science/article/pii/S0300908416301353?via%3Dihub
4
Madhusoodanan Urulangodi, Sebesta M, Menolfi D, Szakal B, Sollier J, Sisakova A, Krejci L, Branzei D, Local Regulation of the Srs2 Helicase by the SUMO-like Domain Protein Esc2 Promotes Recombination at the site of Stalled Replication., Genes and Development, 2015, 29 (19); 2067-2080, https://www.ncbi.nlm.nih.gov/pubmed/26443850
5
Gonzalez-Huici V, Szakal B, Urulangodi M, Psakhye I, Castellucci F, Menolfi D, Rajakumara E, Fumasoni M, Bermejo R, Jentsch S, Branzei D, DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity, EMBO J, 2014, 33(4):327-340, https://www.ncbi.nlm.nih.gov/pubmed/24473148
6
Madhusoodanan UK, Rao DN, Diversity of DNA methyltransferases that recognize asymmetric target sequences, Crit Rev Biochem Mol Biol, 2010, 45(2):125-145., https://www.ncbi.nlm.nih.gov/pubmed/20184512
7
Bist P*, Madhusoodanan UK*, Rao DN., A mutation in the Mod subunit of EcoP15I restriction enzyme converts the DNA methyltransferase to a site-specific endonuclease, J Biol Chem, 2007, 282(6):3520-30, https://www.ncbi.nlm.nih.gov/pubmed/17148461
8
Banerjee D, Jacob J, Kunjamma G, Madhusoodanan UK, Ghosh S., Measurement of urinary hydrogen peroxide by FOX-1 method in conjunction with catalase in diabetes mellitus--a sensitive and specific approach, Clin Chim Acta, 2004, 350(1-2):233-6., https://www.ncbi.nlm.nih.gov/pubmed/15530483
9
Banerjee D, Madhusoodanan UK, Nayak S, Jacob J, Urinary hydrogen peroxide: a probable marker of oxidative stress in malignancy, Clin Chim Acta, 2003, 334(1-2):205-9, https://www.ncbi.nlm.nih.gov/pubmed/12867293
10
Banerjee D, Madhusoodanan UK, Sharanabasappa M, Ghosh S, Jacob J, Measurement of plasma hydroperoxide concentration by FOX-1 assay in conjunction with triphenylphosphine, Clin Chim Acta, 2003, 337(1-2):147-52, https://www.ncbi.nlm.nih.gov/pubmed/14568191