People - Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum (SCTIMST)

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श्री चित्रा तिरुनाल आयुर्विज्ञान और प्रौद्योगिकी संस्थान, त्रिवेंद्रम

विज्ञान एवं प्रौद्योगिकी विभाग, भारत सरकार के अधीन एक राष्ट्रीय महत्व का संस्थान

Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum

An Institution of National Importance, Department of Science and Technology, Govt. of India

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ACADEMIC

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Dr. Anil Kumar P. R.

Scientist 'G' and In-Charge

Phone : +91 471 252 0261 (Desk), +91 471 252 0271 (Lab), Fax:+91 471 2341814.

Email :

Academic Qualification Professional Record Publications

Academic Qualifications

Ph.D in Tissue Engineering; Sree Chitra Tirunal Institute for Medical Sciences & Technology, Kerala, India.;2007.

M. Sc in Biotechnology;Mahatma Gandhi University, Kottayam, Kerala, India.; 1997.

Professional Record

Scientist G, Division of Tissue Culture, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Kerala, India; July 2022 - Present.

Scientist F, Division of Tissue Culture, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Kerala, India; Jan 2018 - July 2022.

Scientist-in-Charge, Division of Tissue Culture, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Kerala, India; Oct 2017 - Present.

Visiting Scientist (Research Fellow); Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, USA; August 2016 - 2018

Scientist E; Division of Tissue Culture, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Kerala, India; Jan 2015 - till date.

Scientist D; Tissue Culture Laboratory, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Kerala, India; Jan 2008 - 2012.

Scientist C; Division of Implant Biology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Kerala, India; Jan 2008 - to date.

Research Fellow - A; Laboratory for Cell and Tissue Engineering, Department of Physiology, National University of Singapore, Singapore; June 2007 - Jan 2008.

Project Scientist; Division of Implant Biology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Kerala, India; June 2006 - May 2007.

The DST-IIPA Gold Medal [2009] by the Department of Science and Technology (DST) sponsored program, 8th foundation training program for scientists and technologists, organized by Indian Institute of Public Administration (IIPA), New Delhi.

Awards

Medi Biotech Award - 2014; Society for Educational and Scientific Research, International Conference on Biosciences: State - of - the - Art Advancements, Kumarakom, Kottayam, Kerala, 11-12 September, 2014.

Bajpai-Saha Award (1st prize) - 2006; International Conference on Design of Biomaterials (BIND-06) and XVII Annual Meeting of Society of Biomaterials and Artificial Organs India, Indian Institute of Technology, Kanpur, India, December 08 - 12, 2006.

Young Scientist Award - 2005; XVII Kerala Science Congress, Trichur, Kerala, India, January 29-31, 2005.

Area of Interest

Broad area of research is Cell Technologies which includes in-vitro tissue biology, biological substitutes and functional tissue engineering. The research interest also involves developing new cell based techniques for testing biomedical devices. The lab has the expertise and facility to isolate, characterize and maintain primary culture of Hepatocytes, Liver Sinusoidal Endothelial Cells, Umbilical Vein Endothelial Cells, Bone Marrow Mesenchymal Stem Cells, Limbal Stem cells, Corneal Endothelial Cells and Skin Keratinocytes

Current studies focus on the development of bioengineered tissues for regenerative medicine as well as for organotypical models. Studies are ongoing in developing 3D in vitro models to bridge the gap between conventional 2D culture and in vivo preclinical experiments. Three Dimensional (3D) Bioprinting is an advanced area of tissue engineering that allows fabrication of biological substitutes with precise geometries harboring living cells. Research on 3D bioprinted tissues for in vitro toxicity screening is ongoing. Development of novel tissue specific bioinks is one of the key aspects of 3D bioprinting. Cell sheet technology is relatively new method in tissue engineering where a thermosensitive polymer grafted surface is used for retrieval of cell monolayer or 3D multilayer without any enzyme treatment. Cells sheet engineering using in-house developed method has been reported for the first time in India. Research is ongoing to address cell sheet transfer to large area tissue defects.

Development of new formulations and new applications of thermoresponsive polymers and bioengineered cell sheet from variety of primary and transformed cells. New ventures are explored to develop functional artificial tissue structures and three dimensional multilayered cell sheets constructs for tissue engineering applications. Efforts are going on to use cell sheet technology and differentiate stem cells such as bone marrow mesenchymal stem cells, adipose derived mesenchymal stem cells, hair follicle stem cells etc to get bioengineered tissues. One of the current researches is to find alternate adult stem cell sources for ocular surface regeneration.

Development of degradable scaffolds for skin regeneration.

Collaboration

Department of Biochemistry, University of Kerala, Thiruvananthapuram, India

National Center for Cell Science, Pune, India

Regional Institue of Ophthalmology, Thiruvananthapuram, India

Wake Forest Institute For Regenrative Medicine, North Caronlina, USA

Indian Institute of Space Science and Technology, Thiruvananthapuram (2009-2012)

Current Activities

Head of Division of Tissue Culture.

In-Charge of 3D Bioprinting & Biofabrication Facility and Confocal Microscopy Facility.

PhD guide, PhD Co-Guide and Faculty for the courses MTech - Clinical Engineering and PhD course work. Doctoral Advisory Committee Member of PhD Program.

Cytotoxicity and cytocompatibility evaluation of biomaterials according to ISO standards

Fabrication of scaffolds for tissue engineering, Cell sheet engineering, In vitro testing models.

Patents

6 (Indian)

Fellowships

Jawaharlal Nehru Memorial Scholarship sponsored by the Jawaharlal Nehru Memorial Fund for partial accomplishment of doctoral studies at National University of Singapore, October 2003 - April 2004.

SCTIMST Institute Fellowship for Doctoral Study, 2001 - 2006

Membership

Life member (2022 onwards) - Additive Manufacturing Society of India - India

Life member (2022 onwards) - Society for Alternatives to Animal Experiments (SAAE) - India

Fellow member (2014 onwards) - Society for Educational and Scientific Research, India.

Life member (2014 onwards) - Kerala Science Academy, India.

Life member - Society of Biomaterials and Artificial Organs India.

Life member - Society for Tissue Engineering and Regenerative Medicine India.

Member (2013 onwards) - The Cytometry Society.

On-going Projects

Pre-validation of in vitro 3D Bioprinted Hepatotoxicity test system, Principal Investigator: [TDF, SCTIMST]: 2021 - 2023

Efficacy Evaluation of 3D Bioprinted Liver Constructs, Principal Investigator: [SERB] : 2021 - 2024.

Cytocompatibility evaluation of biomaterials and devices, Phase Principal Investigator: [Technical Research Center, SCTIMST]: 2016 - 2022

Projects Completed

3D printing of Liver Tissue Constructs for In Vitro Hepatotoxicity Testing, Principal Investigator: [Technical Research Center, SCTIMST] : 2016 - 2018.

An innovative tissue-engineered corneal regenerative therapy derived from a thermoresponsive bio-functionalized polymer and multipotent corneal stromal stem cells - Key team member: [UKIERI-DST] : 2015-2016.

Alternate Adult Stem Cells for Ocular Surface Regeneration - Co- Principal Investigator: [DST] : 2014 ? 2017.

Polymeric platform for developing 3D organotypic culture for in vitro toxicity evaluation - Principal Investigator: [Technology Development fund - SCTIMST] - 2014 ? 2015.

Cell sheet engineering on electrospun scaffolds for efficient cell supply in skin tissue engineering ?- Principal Investigator [DST] ? 2012 ? 2015.

In Vitro alternative test system development for Ocular irritation - Co- Investigator [ICMR] - 2011 - 2014

Differentiation of foetal progenitor cells and fabrication of a prototype of bioreactor for bioartificial liver-- Co-Principal Investigator [DBT] - 2008 ? 2013

Development and Feasibility study of Polymeric Scaffolds for Tissue culture under Simulated Microgravity ? Principal Investigator at SCTIMST [IIST] - 2009 - 2012

In vivo efficacy study of a bioengineered cell sheet in rabbits - Co- Investigator [DBT] - 2009 - 2010

Team

Dr. Naresh Kasoju, Scientist C

Mrs. Sumitha KC, Scientific Assistant (Lab)

Mr. Vinod D, Technical Assistant (Lab) B

Dr. Senthilkumar M, DBT Ramalingaswami Fellow

Mr. Roopesh R. Pai, PhD Student

Mrs. Anupama Sekar J, PhD Student

Ms. Kripamol R, PhD Student

Mr. Seenuvasan R, Technical Assistant (Lab)

Dissertations Supervised - M.Phil

Spectroscopic Analysis of Drugs In Liver Extract - Ms. Ruksana Jalal, St. Mary?s College for Women, Thiruvalla [2022]

Biofabrication of stratified epithelial constructs for tissue engineering - Ms. Niranjana Sudha M.Phil. Biomedical Technology, SCTIMST [2019]

Bio-functionalized electrospun matrix for wound healing application - Ms. Sneha Sundaran P, MPhil Biomedical Technology, SCTIMST [2016]

Fabrication and Characterization of in vitro Skin Tissue Construct Using Stimuli Responsive Modified Culture Surface - Mr. Wulligundam Praveen, MPhil Biomedical Technology, SCTIMST [2012]

Isolation and culture of keratinocytes on modified culture surface for skin tissue engineering, Mr. Karthik N. Ramesh, MPhil Biomedical Technology, SCTIMST [2011]

Optimization of corneal cell culture and generation of multilayered in vitro corneal construct, Mr. Karthik N. Ramesh, MSc Biotechnology [2009]

Publications

Article

Roopesh R Pai , Senthilkumar M, Shiny Velayudhan, A Sabareeswaran, PR Anil Kumar, High-throughput production of liver parenchymal microtissues and enrichment of organ-specific functions in gelatin methacrylamide microenvironment, Biotechnology and Bioengineering, 2022, 119, 1018??? 1032, https://doi.org/10.1002/bit.28010

Athira RK, Geetha G, Anil Kumar PR, Harikrishna Varma PR, Kasoju N, Komath M., Hydroxyapatite cages with aligned pores for bone grafting Seeding of human osteoblast-like cells in vitro and their response in dynamic culture mode., Ceramics International, 2021, 47

Shiny Velayudhan, Shilpa Ajit, Roopesh R. Pai, Ramesh Babu V, Sabareeswaran A and Anil Kumar PR, A gel casting tool for fabrication of three dimensional sandwich in-vitro culture system for cytocompatibility evaluation of hydrogels, International Journal of Pharmaceutical Science and Reserach, 2021, 12(9): 4799-4706

Mohamed Ameer J, Ramesh Babu V, Vinod D, Nishad K.V, Sabareeswaran A, Anil Kumar PR, Naresh Kasoju, Fabrication of co-cultured tissue constructs using a dual cell seeding compatible cell culture insert with a clip-on scaffold for potential regenerative medicine and toxicological screening applications, Journal of Science: Advanced Materials and Devices., 2020, 5(2):207-17.

Venugopal, B., Shenoy, S. J., Mohan, S., Anil Kumar, P. R., and Kumary, T. V, Peripheral Blood As a Source of Stem Cells for Regenerative Medicine: Emphasis Towards Corneal Epithelial Reconstruction???An In Vitro Study, Tissue Engineering and Regenerative Medicine, 2020, 17, 495???510, https://doi.org/10.1007

Balu Venugopal, Sachin J Shenoy, Sumitha Mohan , P R Anil Kumar , T V Kumary, Bioengineered corneal epithelial cell sheet from mesenchymal stem cells, A functional alternative to limbal stem cells for ocular surface reconstruction, J Biomed Mater Res B Appl Biomater, 2020, 108(3):1033-1045, DOI: 10.1002/jbm.b.34455

Das, E.C, Kumary, T.V, Anil Kumar, P.R, and Komath, M, Calcium sulfate-based bioactive cement for periodontal regeneration: An in vitro study, Indian Journal of Dental Research, 2019, 30, 558-567, DOI: 10.4103/ijdr.IJDR_12_18

Jimna Mohamed Ameer , Anil Kumar PR, Naresh Kasoju, Strategies to Tune Electrospun Scaffold Porosity for Effective Cell Response in Tissue Engineering, J Funct Biomater, 2019, 9;10(3):30, DOI: 10.3390/jfb10030030

Das, E. C., Dhawan, S., Babu, J., Anil Kumar, P.R, Kumary, T. V., Haridas, V., and Komath, M, Self-assembling polymeric dendritic peptide as functional osteogenic matrix for periodontal regeneration scaffolds???an in vitro study, Journal of Periodontal Research, 2019, 54, 468-480, https://doi.org/10.1111/jre.12647

Das, E. C., Babu, J., Dhawan, S., Anil Kumar, P.R., Kumary, T. V., Haridas, V., and Komath, M., Synthetic Osteogenic Matrix using Polymeric Dendritic Peptides for treating Human Periodontal defects ??? design and in vitro evaluation, Materials Today: Proceedings, 2019, 15, 199-216, https://doi.org/10.1016/j.matpr.2019.04.192

more...

Mohamed Ali, Anil Kumar PR, James J. Yoo, Faten Zahran, Anthony Atala, Sang Jin Lee, A Photo-Crosslinkable Kidney ECM-Derived Bioink Accelerates Renal Tissue Formation, Adv Healthc Mater, 2019, 6(10): 201800992, DOI: 10.1002/adhm.201800992

Deepa K Raj, Kumary TV, Anil Kumar PR, Development of corneal epithelial cell sheet construct from trans-differentiated bone marrow mesenchymal stem cells, Adv Tissue Eng Regen Med Open Access, 2018, 4(4):127???135, 10.15406/atroa.2018.04.00090

Teng Gao, Gregory J Gillispie, Joshua S Copus, Anil Kumar PR, Young-Joon Seol, Anthony Atala, James J Yoo and Sang Jin Lee, Optimization of gelatin???alginate composite bioink printability using rheological parameters: a systematic approach, Biofabrication, 2018, 10(3), 1758-5090, https://doi.org/10.1088/1758-5090/aacdc7

Mohamed Ali, Anil Kumar PR, Sang Jin Lee and J. D. Jackson, Three-dimensional bioprinting for organ bioengineering: promise and pitfalls, Curr Opin Organ Transplant, 2018, 23(6): 649-656, 10.1097/MOT.0000000000000581

Ambili R, Janam P, Saneesh Babu PS, Prasad M, Vinod D, Anil Kumar PR, Kumary TV, Asha Nair S, Radhakrishna Pillai M, An ex vivo evaluation of the efficacy of andrographolide in modulating differential expression of transcription factors and target genes in periodontal cells and its potential role in treating periodontal diseases, J Ethnopharmacol., 2017, 196, 160-167, doi: 10.1016/j.jep.2016.12.029.

Sundaran PS, Bhaskaran A, Alex ST, Prasad T, Haritha VH, Anie Y, Kumary TV and Anil Kumar PR., Drug loaded microbeads entrapped electrospun mat for wound dressing application, J Mater Sci Mater Med, 2017, 28(6), 88, https://doi.org/10.1007/s10856-017-5893-8

Ambili R, Janam P, Saneesh Babu PS, Prasad M, Vinod D, Anil Kumar PR, Kumary TV, Asha Nair S., Differential expression of transcription factors NF-kappaB and STAT3 in periodontal ligament fibroblasts and gingiva of healthy and diseased individuals, Arch Oral Biol, 2017, 82, 19-26, https://doi.org/10.1016/j.archoralbio.2017.05.010

Saumi Mathews, Tilak Prasad, Balu Venugopal, Anwar Azad Palakkan, Anil Kumar PR and Kumary TV, Standardizing transdifferentiation of rabbit bone marrow mesenchymal stem cells to corneal lineage by simulating corneo- limbal cues, J Stem Cell Res Med, 2017, 2(2), 43374, DOI: 10.15761/JSCRM.1000119.

Wulligundam P, Bernadette K. Madathil, Sajin Raj RG, Kumary TV and Anil Kumar PR, A flexible thermoresponsive cell culture substrate for direct transfer of keratinocyte cell sheets, Biomed Mater, 2017, 12(6), 65012, doi: 10.1088/1748-605X/aa8436.

Bernadette K. Madathil, TV Kumary and Anil Kumar PR, Self Organized Skin Equivalent by Epithelial and Fibroblast Cells on Polycaprolactone Electrospun Mat with Porous Fibers, ATROA, 2017, 3(1), 56, http://medcraveonline.com/ATROA/ATROA-03-00056.pdf

Bernadette K. Madathil, Sneha Sundaran P, Kumary TV, Anugya Bhatt and Anil Kumar PR, Biofunctionalised Polycaprolactone Fibrous Mat as a Transfer Tool for Cell Sheet Engineering, Fibers and Polymers, 2017, 18(11), 2094-2101, http://doi 10.1007/s12221-017-7409-z

Bernadette K. Madathil, TV Kumary and Anil Kumar PR, Self Organized Skin Equivalent by Epithelial and Fibroblast Cells on Polycaprolactone Electrospun Mat with Porous Fibers, Adv Tissue Eng Regen Med Open Access, 2017, 3(1):317???322, 10.15406/atroa.2017.03.00056

Jalaja, K., V.S. Sreehari, P.R. Anil Kumar, and R.J. Nirmala, Graphene oxide decorated electrospun gelatin nanofibers: Fabrication, properties and applications, Materials Science and Engineering: C, 2016, 64, 11-19, https://doi.org/10.1016/j.msec.2016.03.036

Prasad T, Shabeena EA, Vinod D, Kumary TV, Anil Kumar PR., Characterization and in vitro evaluation of electrospun chitosan/polycaprolactone blend fibrous mat for skin tissue engineering, J Mater Sci Mater Med., 2015, 26(1), 5352, https://doi.org/10.1007/s10856-014-5352-8

P.R. Sarika, C.V. Sidhy Viha, R.G. Sajin Raj, Rachel James Nirmala, P.R. Anil Kumar, A non-adhesive hybrid scaffold from gelatin and gum Arabic as packed bed matrix for hepatocyte perfusion culture, Materials Science and Engineering: C., 2015, 46, 341-7, https://doi.org/10.1016/j.msec.2014.10.044

P. R. Sarika, P. R. Anil Kumar, Deepa K. Raj, Nirmala Rachel James, Nanogels based on alginic aldehyde and gelatin by inverse miniemulsion technique: synthesis and characterization, Carbohydrate Polymers, 2015, 119, 118-125, https://doi.org/10.1016/j.carbpol.2014.11.037

Sarika, P.R., N.R. James, N. Nishna, P.R. Anil Kumar, and D.K. Raj, Galactosylated pullulan?curcumin conjugate micelles for site specific anticancer activity to hepatocarcinoma cells, Colloids and Surfaces B: Biointerfaces, 2015, 133(0), 347-355, https://doi.org/10.1016/j.colsurfb.2015.06.020

Shiny Velayudhan, Anil Kumar PR and Prabha D. Nair, A novel, single step, highly sensitive in-vitro cell-based metabolic assay using honeycomb microporous polymer membranes, J. Biomed. Nanotechnol, 2015, 11, 590-599., http://dx.doi.org/10.1166/jbn.2015.2066

K. Jalaja, P.R. Anil Kumar, Tuli Dey, Subhas C. Kundu, Nirmala R. James, Modified dextran cross-linked electrospun gelatin nanofibres for biomedical applications, Carbohydrate Polymers 12/2014, 2014, 114, 467-475, https://doi.org/10.1016/j.carbpol.2014.08.023

Anwar Azad Palakkan, Anil Kumar PR and Kumary TV, An In Vitro Fluorometric Assay for Evaluating Functional Polarity of Hepatocyte, Int. J. Bioassays, 2014, 3 (1), 1630-1636., http://www.ijbio.com/index.php/ijb/article/view/2

Palakkan AA, Raj DK, Rojan J, Raj R G S, Anil Kumar PR, Muraleedharan CV, Kumary TV., Evaluation of polypropylene hollow-fiber prototype bioreactor for bioartificial liver, Tissue Eng Part A., 2013, 19(9-10), 1056-66, https://doi.org/10.1089/ten.TEA.2012.0332

Bernadette K. Madathil, PR Anil Kumar, and TV Kumary,, N-Isopropylacrylamide-co-glycidylmethacrylate as a Thermoresponsive Substrate for Corneal Endothelial Cell Sheet Engineering,, BioMed Research International, 2014, Article ID 450672, 7 page, http://www.hindawi.com/journals/bmri/2014/450672/

P.R. Sarika, Kuriakose Cinthya, A. Jayakrishnan, P.R. Anil Kumar*, Nirmala Rachel James*, Modified gum arabic cross-linked gelatin scaffold for biomedical applications, Materials Science and Engineering C, 2014, 43: 272-279., http://www.ncbi.nlm.nih.gov/pubmed/25175214

Abhineeshbabu Thottiparambil, Anil Kumar PR, Lakshmi Chakkumkumarath, Styrylcyanine-based ratiometric and tunable fluorescent pH sensors, RSC Adv., 2014, 4, 56063-56067., DOI: 10.1039/C4RA10959G

Anwar A. Palakkan, David C. Hay, Anil Kumar PR, Kumary TV, James A. Ross, Liver tissue engineering and cell sources: issues and challenges, Liver Int., 2013, 33(5), 666-76, DOI: 10.1111/liv.12134

Padmaja Parameswaran Nampi, Cheranellore Chandrasekharan Kartha, Gin Jose, Anil Kumar P.R., Thapasimuthu Anilkumar, Harikrishna Varma, Sol?gel nanoporous silica as substrate for immobilization of conjugatedbiomolecules for application as fluorescence resonance energy transfer (FRET) based biosensor, Sensors and Actuators B, 2013, 185, 252? 257, http://dx.doi.org/10.1016%2Fj.snb.2013.04.067

Joseph, N., Anil Kumar P.R and T. V. Kumary., Tunable Stimuli-Responsive Polymers for Cell Sheet Engineering, Regenerative Medicine and Tissue Engineering - Cells and Biomaterials. D. Eberli. Rijeka, 2011, Ch 23, 503-512, DOI: 10.5772/24297

Sunny, M., Vincy, P., Anil Kumar, P. and Ramesh, P.,, Porous composites of hydroxyapatite-filled poly[ethylene-co-(vinyl acetate)] for tissue engineering, Polym. Int., 2011, 60, 51?58, doi:10.1002/pi.2973

Nithya Joseph, Anil Kumar PR, Tilak Prasad, Leena Joseph, Sreenivasan.K, and Kumary TV, Intelligent Thermoresponsive Substrate from Modified Over Head Projection Sheet as a Tool for Construction and Support of In Vitro Corneal Cell Sheet, Tissue Eng Part C Methods., 2011, 17(2), 181-91, https://doi.org/10.1089/ten.TEC.2009.0783

Nithya Joseph, Tilak Prasad, Vidya Raj, Anil Kumar PR, K. Sreenivasan and T V Kumary, A Cytocompatible Poly(N-isopropylacrylamide-co-glycidylmethacrylate) Coated Surface as New Substrate for Corneal Tissue Engineering, Journal of Bioactive and Compatible Polymers, 2010, 25: 58-74., http://jbc.sagepub.com/content/25/1/58.short

Thomas N. Abraham, Vidya Raj, Tilak Prasad, Anil Kumar PR, K. Sreenivasan, T. V. Kumary, A Novel Thermoresponsive Graft Copolymer Containing Phosphorylated HEMA for Generating Detachable Cell Layers, J Appl Polym Sci., 2010, 115, 52?62

Raquel Magalhales*, Anil Kumar PR*, FengWen, Xuying Zhao, Hanry Yu, Lilia L. Kuleshova, The use of vitrification to preserve primary rat hepatocyte monolayer on collagen coated poly(ethylene-terephthalate) surfaces for a hybrid liver support system,, Biomaterials, 2009, 30(25), 4136-42

Anil Kumar PR, Sreenivasan K and Kumary TV, An alternate method for grafting thermoresponsive polymer for transferring in vitro cell sheet structures, Journal of Bioactive and Compatible Polymers, 2007, 105(4), 2245-2251

Anil Kumar PR, Varma HK and Kumary TV, Cell patch seeding and functional analysis of cellularized scaffolds for tissue engineering, Biomed. Mater, 2007, 2: 48-54., http://iopscience.iop.org/1748-605X/2/1/008/pdf/bmm7_1_008.pdf

Kumar, PR; Varma, HK; Kumary, TV, Rapid and complete cellularization of hydroxyapatite for bone tissue engineering, Acta Biomaterialia, 2005, 1; 545-552, http://dx.doi.org/10.1016/j.actbio.2005.05.002

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Book Chapter

Bernadette K. Madathil, P. R. Anil Kumar, Vinoy Thomas, and Shiny Velayudhan, Nanomaterial-Based Bio Scaffolds for Enhanced Biomedical Applications, Bio-manufactured Nanomaterials: Perspectives and Promotion, 2021, Ed Kaushik Pal, Springer

Senthilkumar Muthusamy, Shiny Velayudhan and Anil Kumar PR, Hydrogel Systems for Tissue Engineering, In: Handbook of Research on Nano-Drug Delivery and Tissue Engineering Guide to Strengthening Healthcare Systems, 2021, Apple Academic Press, USA

Balu V. Gopal, Bernadette K. Madathil, P.R. Anil Kumar, Stem cell based therapeutic approaches toward corneal regeneration, Biointegration of Medical Implant Materials, 2020, Elsevier Ltd, https://doi.org/10.1016/B978-0-08-102680-9.00011-1

Gergory J. Gillipse, Jihoon Park, Joshua S Copus,Anil Kumar PR, James J Yoo, Anthony Atala, Sang Jin Lee, Three Dimensional Tissue and Organ Printing in Regenerative Medicine, In: Principles of Regenerative Medicine, Ed: Anthony Atala, Robert Lanza, Antonios G. Mikos, Robert Nerem, 2019, 3rd Edn

Shiny Velayudhan and Anil Kumar P R, Three Dimensional Bioprinting - A Closer Step Towards Creating Customized Tissues and Organs, Spinco Biotech Cutting Edge, 2018, 34-38

Abstract

Anil Kumar P.R., Mohamed Ali, Sang Jin Lee, James Yoo and Anthony Atala, 3D bioprinting of human kidney construct: A step towards solid organ printing, Tissue Engineering Part A, 2017, 23(S1), https://www.liebertpub.com/doi/full/10.1089/ten.tea.2017.29003.abstracts

People - Division Of Tissue Culture

Dr. Anil Kumar P. R.
Dr. Naresh K

This is the official Website of Sree Chitra Tirunal Institute for Medical Sciences & Technology under Department of Science & Technology, Government of India.

Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum
Thiruvananthapuram - 695 011, Kerala, India.
Email :sct@sctimst.ac.in
Phone : 91-471-2443152 Fax : 91-471-2446433
PAN NO: AAAJS0437M
TAN : TVDS00986G
GSTIN NO: 32AAAJS0437M1Z4 Date : 28-06-2017

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