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BIOMEDICAL TECHNOLOGY
BIOMATERIALS GROUP

Bio Ceramics Laboratory
This laboratory mainly concentrates on the research and development of various bone graft materials such as hydroxyapatite porous granules, bioactive glass and their composites, calcium phosphate cements etc. Research is also on going in the areas of bioceramic-polymer composites and biomimetic processing. The laboratory is equipped with X-Ray Diffractometer, Microhardness Tester etc.

Scanning Electron Microscope Facility
This facility has a Scanning Electron Microscope attached with an Energy Dispersive X-Ray Analysis (EDS) system with OXFORD Link Ultracool Detector, having a resolution of 133eV/Mn.

Biosurface Technology Division
The basic activities of the laboratory are to understand the blood/tissue material interactions at the interface and develop modified surfaces for various biomedical applications such as haemoperfusion column, bioprosthetic heart valve etc. Laboratory is also interested in modifying interfaces towards drug release studies including oral insulin delivery system, artificial skin, transdermal delivery systems and possible peptide delivery system based on porous hydroxyapatite microspheres.

Polymer Division
The major activities of the laboratory are development of implantable polymeric materials for biomedical applications like high flex life polyurethane - urea for heart valve and cardiac pump, bioassimilable and injectable unsaturated polyester bone cement for orthopaedic applications, bioassimilable unsaturated polyester-copolymer as blood-vessel barrier to thrombosis etc.


Laboratory for Polymer Analysis

The laboratory's activities are analytical methods development, molecular imprinting, cyclodextrins, modification of polymers, development of super absorbing materials for ophthalmic and other medical applications, development of antibacterial polymers, metal containing polymers and porous materials for cell encapsulation or cell exclusion, processes to impart antibacterial properties and materials for guided tissue regeneration. Analytical facilities include FTIR Spectroscopy, Thermal Analysis, UV Spectroscopy etc.


Division of Tissue Engineering and Regeneration Technologies

Tissue engineering with a long term goal of addressing the shortage of donor organs for transplantation,by designing suitable organs / biological substitutes is a major thrust area of this Division.The division has ambitious research programmes to create “organs” such as pancreas, cartilage, blood vessels etc,that may be available “off the shelf”’ and impact clinical applications.Current major research programs of the division have been directed to develop (a) novel,biodegradable and bio mimetic "designer" scaffolds (b) understand the regeneration processes using adult cells and directed stem cell differentiation,and (c)delineate the molecular pathways that regulates the growth factors and other molecules or drugs to promote regeneration.. Other areas of our interest deal with usage of bioreactors, wherein the “in vivo” environment is recapitulated and monitored “in vitro,” while exerting physiologically relevant mechanical and biochemical stimuli to guide neo tissue development.  The division also contributes to other lab and institutional programs (e.g. lung, bone) with “designer” scaffolds. Development of biopolymer composites for medical applications is another important area of research. Scaffolds made by conventional techniques and electro spinning as well as regulator combinations generated by our division, find additional applications in drug delivery, wound healing and haemostats.The division has been supported with project grants from DST, DBT Govt of India, and KSTEC, Kerala, been the Nodal centre for the Joint Indo-US Centre for Stem Cells & Tissue Engineering supported by IUSSTF and is the  Lead for the Centre of Excellence in Tissue engineering program with support from DBT, Govt of India.

 
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